University of Southampton

university logo copyThe University of Southampton’s role within the Wound Prevention and Treatment HTC is led by Dan Bader, Professor of Bioengineering and Tissue Health at the Faculty of Health Sciences.

Since beginning his role in 2011, Prof. Bader has established a multidisciplinary team focused on maintaining skin health and preventing pressure ulcers as part of the clinical academic facility based at Southampton General Hospital.

The team includes a research fellow (physiotherapist), a part-time Senior Nurse from the Netherlands (a current EPUAP Trustee), 5 PhD students with backgrounds in hospital/community nursing, physiotherapy and physiology to complement existing academics with expertise in physiological monitoring and continence technologies.

Uni of Southampton

Role within the HTC

The University of Southampton’s main focus for the HTC is on bioengineering strategies in pressure ulcer prevention.

Key projects

Currently, the University of Southampton is working on a number of projects within wound care including;

  • Establishing objective threshold levels to indicate compromise to skin integrity
  • Evaluation of individual risk of tissue breakdown in patients during prolonged surgical procedures
  • Monitoring movement strategies for chair and wheelchair-bound subjects and prescribing appropriate pressure-relief regimens.
  • Provision of optimal design features for pressure redistribution support surfaces – the concept of a ‘personalised support surface’ to match the physiological response of individual subjects
  • The role of medical devices in creating mechanical trauma of soft tissues, for example, in paediatric IC units

Areas of expertise

Sensor development, physiological monitoring, devices and support system assessment, test protocols.

Services provided

The University of Southampton can assist with:

  • Medical device design and evaluation
  • in-vitro test modelling and testing
  • Sensing
  • Pressure ulcer prevention

Selected publications

Chai CY, Bader DL. (2013) The physiological response of skin tissues to alternating support pressures in able-bodied subjects. J Mech Behav Biomed Mater. doi:pii: S1751-6161(13)00179-3. 10.1016/j.jmbbm.2013.05.014

Oomens CWJ, Zenhorst W, Broek M, Hemmes B, Poeze M, Brink PRG, Bader DL. (2013) A numerical study to analyse the risk for pressure ulcer development on a spine board. Clinical Biomechanics 28, 736-42

Porter-Armstrong AP, Adams C, Moorhead AS, Donnelly J, Nixon J, Bader DL, Lyder C, Stinson MD (2013) Do high frequency ultrasound images support clinical skin assessment? ISRN Nurs. 2013; 314248. doi: 10.1155/2013/314248. Epub 2013 Feb 21

Loerakker S, Huisman ES, Seelen HAM, Glatz JFC, Baaijens FPT, Oomens CW, Bader DL (2012) Plasma variations of biomarkers for muscle damage in able-bodied and spinal cord injured subjects. J.Rehab.Res Dev. 49(3):1-12

Loerakker S, Manders E, Strijkers GJ, Nicolay K, Baaijens FP, Bader DL, Oomens CW. (2011) The effects of deformation, ischemia, and reperfusion on the development of muscle damage during prolonged loading. J Appl Physiol. 111(4):1168-77.

Loerakker S, Stekelenburg A, Strijkers GJ, Rijpkema JJ, Baaijens FP, Bader DL, Nicolay K, Oomens CW (2010) Temporal effects of mechanical loading on deformation-induced damage in skeletal muscle tissue. Ann Biomed Eng. 38(8):2577-87.

Oomens CW, Loerakker S, Bader DL (2010).The importance of internal strain as opposed to interface pressure in the prevention of pressure related deep tissue injury. J Tissue Viability. 19(2):35-42.

Cornelissen LH, Bronneberg D, Bader DL, Baaijens FP, Oomens CW (2009) The transport profile of cytokines in epidermal equivalents subjected to mechanical loading. Ann Biomed Eng. 37(5):1007-18.

Stekelenburg A, Gawlitta D, Bader DL, Oomens CW (2008) .Deep tissue injury: how deep is our understanding? Arch Phys Med Rehabil. 89(7):1410-3.

Bader, DL, Bouten, CVC, Oomens, CWJ,Colin D. (2005) Editors In: Pressure Ulcer Research: Current and Future Perspectives Springer-Verlag: Berlin pp 1-381 ISBN 3-540-25030-1


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